The Strength of Calcium
with the Purity of Genistein
Pay no more than $45 on every Fosteum prescription

About

Frequently Asked Questions: Fosteum PLUS (fos-tee-um)

  1. Is Fosteum PLUS safe?
  2. What are osteopenia and osteoporosis?
  3. How do I know if I have osteopenia or osteoporosis?
  4. What is a T-score and how is it measured?
  5. If I have a lot of risk factors for osteoporosis, can I take Fosteum PLUS?
  6. What can I do to reduce my risk of osteopenia and osteoporosis?
  7. How does Fosteum PLUS work?
  8. Who should take Fosteum PLUS?
  9. Who should not take Fosteum PLUS?
  10. How should I take Fosteum PLUS?
  11. What are the possible side effects of Fosteum PLUS?
  12. Does Fosteum PLUS have any effect on hot flashes?
  13. What if I miss my dose of Fosteum PLUS?
  14. What are the ingredients in Fosteum PLUS?
  15. What if I'm allergic to soy?
  16. What if I have other questions about Fosteum PLUS?
  17. General Information about Fosteum PLUS

What is Fosteum PLUS?

Fosteum PLUS is a specially formulated prescription medical food, developed from natural ingredients, that is used for the clinical dietary management of osteopenia and osteoporosis. Fosteum PLUS is indicated when a good diet and supplements like calcium and vitamin D are not enough, but you are not ready for drugs with their potential for side effects. Learn more about Fosteum PLUS.

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Is Fosteum PLUS safe?

All the ingredients in Fosteum PLUS are GRAS (Generally Accepted As Safe). GRAS is a strict FDA designation that applies to all food ingredients and indicates that the ingredient is safe for its intended use. All medical foods must contain GRAS ingredients. In addition, Fosteum PLUS has been tested for safety in clinical trials. In three studies over one, two and three years, safety was determined by tracking vaginal bleeding and by measuring uterine endometrial thickness (vaginal bleeding and thickening indicate possible uterine cancer) and by regular measurement of breast density (increased density indicates possible breast cancer). No changes were seen in breast or uterus measurements in either the genistein group or the placebo group. Cardiac safety has also been studied and the results were either improved or no change, indicating that Fosteum PLUS poses no danger to the heart.

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What are osteopenia and osteoporosis?

Osteopenia and osteoporosis are grades of the same condition indicating degrees of bone loss. Osteopenia is the first condition. If it goes untreated, it can progress to osteoporosis. Learn more about osteoporosis and osteopenia.

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How do I know if I have osteopenia or osteoporosis?

The best way to know is to KNOW YOUR T-SCORE. That means you should have a dual energy x-ray absorptiometry (DXA) and get your doctor to tell you what your score is at spine and hip. That is your T-score. If your T-score at any site is -1.0 to 2.5, you have osteopenia (your bone mass is lower than average). If your T-score is worse than 2.5, you have osteoporosis.

If you do not know your T-score, at first you would not know if you are losing bone because osteopenia and osteoporosis have no symptoms in the beginning. That's why osteoporosis is called "The Silent Disease". There is no pain or feeling of any kind when osteoporosis begins. Later, after a lot of bone is lost,

  • You may break a bone, even from simple everyday movements.
  • Broken bones may cause you to require assistance with routine living. The majority of people over 50 who break a hip lose their independence, and 20% die in the year following the break.
  • You may 'shrink' (get shorter) because of broken bones in your spine.
  • You may get a 'dowager's hump', a curve to your spine caused by broken bones in your spine.
  • You may develop severe back pain that keeps you from doing things you want to do.

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What is a T-score and how is it measured?

A T-score is a measure of how dense your bone is. Higher numbers usually mean stronger bone. The T-score is determined by comparing your bone to the bone of a large group of healthy 30 year olds. The difference in standard deviations between your result and the young average result is a T-score. If your bone is the same as the young average the result would be 0. If your result is lower than the young average, your T-score would be a minus number. A score between -1.0 and -2.5 indicates osteopenia. A score lower than -2.5 indicates osteoporosis.

If I have a lot of risk factors for osteoporosis, can I take Fosteum PLUS?

If you and your doctor agree that early intervention is appropriate, you certainly can take Fosteum PLUS.

Talk to your doctor about Fosteum PLUS.

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What can I do to reduce my risk of osteopenia and osteoporosis?

You can change a lot of things that affect your bone health, like:

  • If you smoke, stop.
  • Exercise. When you do weight bearing exercise it stimulates your bones to become stronger. This may be walking, stair climbing, dancing or lifting weights. The weights do not have to be heavy. Lifting even a one pound weight will help to increase bone strength.
  • Do not drink more than one or two alcoholic drinks each day.
  • Make sure you eat a healthy diet and get enough calcium and vitamin D3.

Learn more about about Fosteum PLUS works.

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How does Fosteum PLUS work?

The genistein in Fosteum PLUS decreases the activity of cells that break down bone and stimulates the cells that build up bone. This restores a more normal balance of bone breakdown and formation (also called bone turnover) and results in increased bone mass. Increased bone mass may lead to a reduced risk of fracture over time. You won't feel a change, but your BMD may increase over time. The other ingredients in Fosteum PLUS either help the genistein work better or are included for your safety or convenience, like calcium and vitamin D and MK-7.

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Who should take Fosteum PLUS?

Anyone at risk for bone loss may take Fosteum PLUS.

Women approaching menopause (the change), women in menopause and women after menopause may take Fosteum PLUS.

Women who have had surgery to remove their ovaries may take Fosteum PLUS. Read more about taking Fosteum PLUS

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Who should not take Fosteum PLUS?

Do not take Fosteum PLUS:

  • If you are allergic to any ingredient in Fosteum PLUS. (See: What are the ingredients in Fosteum PLUS?)
  • If you're pregnant or nursing (because it has not been tested in pregnant or nursing women.)
  • If you are under 18 years of age (because it has not been tested in pediatric patients.)
  • If you are taking hormone therapy or a SERM (Selective Estrogen Receptor Modulator, such as Evista®) for osteoporosis (because it has not been tested in combination with these products).

Talk to your doctor about Fosteum PLUS

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How should I take Fosteum PLUS?

  • Take Fosteum PLUS with or without food. Take it with any beverage you like, even grapefruit juice or coffee, if you would normally drink grapefruit juice or coffee.
  • You do not have to stand or sit after taking Fosteum PLUS. You may take Fosteum PLUS and lie down immediately if you wish.
  • Decide on convenient times to take Fosteum PLUS. Take one capsule approximately every 12 hours; for example, when you get up in the morning and after your evening meal, or any other combination that works for your schedule and makes it easy to remember.

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What are the possible side effects of Fosteum PLUS?

A possible positive effect of Fosteum PLUS is a reduction in the number and intensity of hot flashes over time. In clinical studies 70% of women who had hot flashes reported a reduction in the number and/or intensity of the hot flashes with time. Other possible side effects include breast tenderness that goes away with time, and mild to moderate GI symptoms including: upset stomach, nausea, stomach/abdominal pain and constipation.

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Does Fosteum PLUS have any effect on hot flashes?

Frequency and severity of hot flashesIn the clinical study, all women were asked to keep a journal describing any symptoms that they may have. This should include GI effects, hot flashes, etc. An important point is that the women were never told that hot flashes were being studied. They were only told that bone was being studied. The investigators examined the journals and then followed the women who reported more than five hot flashes a day in their journals at the start of the trial.

This is important because hot flash studies are notorious for high placebo effect - that is, a large number of the patients taking placebo report reductions in hot flashes. Since these patients were never told that hot flashes were being studied, placebo effect was minimal. This says that the genistein in Fosteum PLUS was responsible for the reduction in the number and the intensity of the hot flashes.

In clinical trials, the women who suffered from hot flashes and took the genistein with calcium and vitamin D3 in Fosteum PLUS had fewer hot flashes and the hot flashes they did have were not as strong. This improved hot-flash effect of the genistein in Fosteum PLUS became better the longer they took the product.

Talk to your doctor about Fosteum PLUS.

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What if I miss my dose of Fosteum PLUS?

If you miss a dose you may take it when you remember. If it is very close to the time for your next dose, wait and take the next dose on schedule.

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What are the ingredients in Fosteum PLUS?

Fosteum PLUS contains dicalcium malate, pentacalcium hydroxide triphosphate, phosphate, genistein aglycone (naturally isolated from a non-soy source), citrated zinc bisglycinate, trans-menaquinone-7, cholecalciferol, micro-crystaline cellulose, magnesium stearate, silicon dioxide, and sodium copper chlorophyllin in a gelatin capsule with titanium dioxide as coloring. Fosteum PLUS does not contain fructose, glucose, sucrose, lactose, gluten, maltodextrin, tree nuts, peanuts, flavors or products of animal or seafood origin. Fosteum PLUS is suitable for vegans if the capsule is opened and the contents of the capsule sprinkled over soft food, such as applesauce

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What if I'm allergic to soy?

Since the genistein in Fosteum PLUS is naturally isolated from a non-soy source, your soy allergy should be no problem. If you are allergic to any ingredient in Fosteum PLUS, you should not take Fosteum PLUS.

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What if I have other questions about Fosteum PLUS?

If you need more information, ask your health care provider or pharmacist. They can give you information written for health care professionals. You may also review the other sections of this website.

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General Information about Fosteum PLUS

Store Fosteum PLUS at room temperature between 59°F and 86°F (15°C and 30°C).

Keep out of the reach of children.

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  • Why Fosteum Plus?
  • Why Medical Foods?
Why Fosteum Plus?
Fosteum PLUS is the only product available clinically proven to manage bone loss that offers calcium, phosphate and MK-7 in a single capsule along with genistein, citrated zinc bisglycinate and vitamin. Each ingredient is chosen for its specific action in helping to build quality bone.
Why Medical Foods?
Medical foods are an official Food and Drug Administration (FDA) category of products that must have therapeutic value based on recognized science. The name “medical foods” was chosen by the U.S. Congress. All medical foods must meet the distinctive dietary requirements of a particular disease.